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JoVE Journal
Immunology and Infection

This content is Open Access.

RNAi Screening for Host Factors Involved in Vaccinia Virus Infection using Drosophila Cells
 
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RNAi Screening for Host Factors Involved in Vaccinia Virus Infection using Drosophila Cells

Article DOI: 10.3791/2137
August 25th, 2010

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Summary August 25th, 2010

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Click here for the English version.

Novel host factors involved in viral infection can be identified through cell-based genome-wide loss of function RNAi screening. A Drosophila cell culture model is particularly amenable to this approach due to the ease and efficiency of RNAi. Here we demonstrate this technique using vaccinia virus as an example.

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