Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Immunology and Infection / Passive Administration of Monoclonal Antibodies…
JoVE Journal
Immunology and Infection

A subscription to JoVE is required to view this content.

JoVE Journal Immunology and Infection
Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens
Use of the Invertebrate Galleria mellonella as an Infection Model to Study the Mycobacterium tuberculosis Complex
Journal (Immunology and Infection)
Use of the Invertebrate Galleria mellonella as an Infection Model to Study the Mycobacterium tuberculosis Complex
Enteric Bacterial Invasion Of Intestinal Epithelial Cells In Vitro Is Dramatically Enhanced Using a Vertical Diffusion Chamber Model
Journal (Immunology and Infection)
Enteric Bacterial Invasion Of Intestinal Epithelial Cells In Vitro Is Dramatically Enhanced Using a Vertical Diffusion Chamber Model
 

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens

Article DOI: 10.3791/2532-v • 09:58 min • February 14th, 2011
February 14th, 2011 •
1, 1, 1
1Department of Microbiology and Immunology, Albert Einstein College of Medicine

Chapters

Summary
Automatic Translation

C57BL/6 mice have been used to study Hc pathogenesis and provide the best model. We are exploring the potential benefits of humoral immunity against this fungus and generated several mAbs [to histone H2B and a heat shock protein 60kDa] that we tested for their protective efficacy after intraperitoneal administration.

Tags

Passive Administration Monoclonal Antibodies H. Capsulatum Fungal Pathogens Histoplasmosis Antibody Therapy Virulence Factors MAbs Generation Solid Phase ELISA System Splenocytes Fusion C57BL/6 Mice Infection Assessment Mortality As An Endpoint Colony Forming Units (CFU) Survival Studies Intervention Efficacy Vaccine Efficacy Virulence Testing
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter