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JoVE Journal
Immunology and Infection

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协同刺激信号封锁的同种抗原刺激诱导人外周血单个核细胞同种异体抗原特异性无能
 
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协同刺激信号封锁的同种抗原刺激诱导人外周血单个核细胞同种异体抗原特异性无能

Article DOI: 10.3791/2673-v 11:55 min March 14th, 2011
March 14th, 2011

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Summary

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Click here for the English version.

本文介绍了一个简单的方法诱导人外周血单个核细胞同种异体抗原特异性无能。该技术可应用于临床,产生非同种异体的供体细胞。这些细胞输注可以提高免疫功能重建和减少异基因造血干细胞移植后的毒性。

Tags

免疫学,第49期,异基因干细胞移植,alloreactivity,移植物抗宿主病,T细胞共刺激,无能,混合淋巴细胞反应。
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