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JoVE Journal
Bioengineering

This content is Open Access.

Biomolecular Detection employing the Interferometric Reflectance Imaging Sensor (IRIS)
 
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Biomolecular Detection employing the Interferometric Reflectance Imaging Sensor (IRIS)

Article DOI: 10.3791/2694
May 3rd, 2011

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Summary May 3rd, 2011

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Click here for the English version.

Quantitative, high-throughput, real-time, and label-free biomolecular detection (DNA, protein, etc.) on SiO2 surfaces can be achieved using a simple interferometric technique which relies on LED illumination, minimal optical components, and a camera. The Interferometric Reflectance Imaging Sensor (IRIS) is inexpensive, simple to use, and amenable to microarray formats.

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