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Neuroscience

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Entrega génica eficaz en los territorios del SNC múltiples utilizando In Utero La electroporación
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Entrega génica eficaz en los territorios del SNC múltiples utilizando In Utero La electroporación

Article DOI: 10.3791/2957
June 23rd, 2011 •
1, 2, 1, 1,2, 1, 2, 1
1Department of Biochemistry and Molecular Biology, Hotchkiss Brain Institute, Alberta Children’s Hospital Research Institute, University of Calgary, 2Department of Medical Genetics, Alberta Children’s Hospital Research Institute, Hotchkiss Brain Institute, University of Calgary

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June 23rd, 2011

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En el útero de la electroporación permite la entrega rápida de genes en un espacio-temporal y controlado de manera en el desarrollo del sistema nervioso central (SNC). Aquí se describe una muy adaptable en el protocolo de electroporación in utero que puede ser utilizado para entregar las construcciones de expresión en múltiples dominios del SNC embrionario, incluyendo el telencéfalo, diencéfalo y la retina.

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