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Journal / Immunology and Infection / Sezieren Host-Virus-Interaktion in Lytic…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Sezieren Host-Virus-Interaktion in Lytic Replikation von einem Modell Herpesvirus
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Sezieren Host-Virus-Interaktion in Lytic Replikation von einem Modell Herpesvirus

Article DOI: 10.3791/3140-v • 11:29 min • October 7th, 2011
October 7th, 2011 •
1, 2
1Center for Autophagy Research, Department of Internal Medicine, UT Southwestern Medical Center, 2Department of Microbiology, UT Southwestern Medical Center

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Wir beschreiben ein Protokoll zu den wichtigsten Aufgaben der Host Signalmoleküle in lytische Replikation eines Modells Herpesvirus, gamma Herpesvirus 68 (γHV68) zu identifizieren. Mit Hilfe genetisch veränderter Mauslinien und embryonale Fibroblasten zur γHV68 lytische Replikation, erlaubt das Protokoll sowohl phänotypische Charakterisierung und molekulare Vernehmung von Virus-Wirt-Interaktionen in lytischen Replikation.

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Immunologie Herpesvirus gamma Herpesvirus 68 γHV68 Signalwege Wirt-Virus-Interaktion lytischen Replikation
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