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Parkinson Hastalığının tek taraflı lezyonlanmıştır 6-OHDA Mouse Model Geliştirme
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Parkinson Hastalığının tek taraflı lezyonlanmıştır 6-OHDA Mouse Model Geliştirme

Article DOI: 10.3791/3234-v • 10:09 min • February 14th, 2012
February 14th, 2012 •
1, 1, 1
1Centre for Neurobiology of Stress, Dept Biological Sciences, University of Toronto at Scarborough

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Bir protokol unilateral 6-OHDA lezyonlar, farelerde medyal önbeyin demet gerçekleştirmek için tarif edilmektedir. Bu yöntem, striatal dopamin ve 90,63>% 95 kaybı gösteren hayatta kalan hayvanların% 89 ile düşük mortalite oranı (% 13.3) ±% -4,02, lezyonun tarafa doğru ipsiversive dönme önyargı vardır.

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Tek taraflı Tıp Sayı 60 fare 6-OHDA Parkinson hastalığı medial ön beyin demeti,
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