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FSL Constructs
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FSL Constructs: A Simple Method for Modifying Cell/Virion Surfaces with a Range of Biological Markers Without Affecting their Viability

Article DOI: 10.3791/3289-v • 09:39 min • August 5th, 2011
August 5th, 2011 •
1, 2, 1, 1
1Biotechnology Research Institute, AUT University and KODE Biotech Ltd, 2Shemyakin Institute of Bioorganic Chemistry RAS, Moscow, Russia

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Function-Spacer-Lipid (FSL) constructs allow the surface characteristics of living cells and virions to be modified without loss of vitality. The method requires only simple contact of an FSL construct solution with a cell/virion and spontaneous and stable surface incorporation occurs.

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FSL Constructs Biological Markers Modify Cell Surfaces Modify Virion Surfaces Viability Genetic Engineering Covalent Attachment Chemical Moieties Surface Modification Harmlessly Modify Cell Surfaces KODE Technology Functional Head Group Spacer Lipid Tail Dispersible In Water Membrane Incorporation Saccharides Blood Group-related Determinants Sialic Acids Hyaluronan Polysaccharides Fluorophores Biotin Radiolabels Peptides
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