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Uncoating는 HIV - 1 수명주기의 초기 단계에 필수적인 단계이며 capsid 쉘의 해체와 바이러스 ribonucleoprotein 복합 (vRNP)의 출시로 정의됩니다. 여기, 우리는 HIV - 1 virions에서 그대로 코어를 분리 및 그들의 uncoating을 quantifying 기술을 입증