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Immunology and Infection

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JoVE Journal Immunology and Infection
Met behulp van reverse genetics aan de NSS-gen van de Rift Valley Fever virus MP-12 Strain om Vaccine veiligheid en effectiviteit te verbeteren manipuleren
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Met behulp van reverse genetics aan de NSS-gen van de Rift Valley Fever virus MP-12 Strain om Vaccine veiligheid en effectiviteit te verbeteren manipuleren

Article DOI: 10.3791/3400-v • 09:13 min • November 1st, 2011
November 1st, 2011 •
1, 1, 1, 1
1Department of Pathology, University of Texas Medical Branch

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De reverse genetics systeem voor de Rift Valley koorts virus MP-12 vaccinstam is een handig hulpmiddel voor het creëren van extra MP-12 mutanten met verhoogde verzwakking en immunogeniciteit. We beschrijven het protocol te genereren en karakteriseren NSS mutante stammen.

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Immunologie Rift Valley koorts virus reverse genetics NSS MP-12 de ontwikkeling van vaccins
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