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High Content Screening in Neurodegenerative Diseases
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High Content Screening in Neurodegenerative Diseases

Article DOI: 10.3791/3452-v • 13:32 min • January 6th, 2012
January 6th, 2012 •
1, 2, 1
1Department of Clinical Genetics, VU University Medical Center, 2Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam

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Wir beschreiben eine Methode kombiniert automatisierte Zellkultur mit High-Content-Bildgebung zur Visualisierung und Quantifizierung von mehreren zellulären Prozessen und Strukturen, in einem High-Throughput Weise. Solche Methoden können in der weiteren funktionellen Annotation von Genomen Hilfe sowie zu identifizieren Krankheit Gen-Netzwerke und mögliche Angriffspunkte für Medikamente.

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Medizin High-Throughput-Screening High-Content Screening Neurodegeneration automatisierte Zellkultur Parkinson-Krankheit
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