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Journal / Immunology and Infection / Effektiv Rekombinant Parvovirus Produktion ved…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Effektiv Rekombinant Parvovirus Produktion ved hjælp af adenovirusafledte Systems
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Effektiv Rekombinant Parvovirus Produktion ved hjælp af adenovirusafledte Systems

Article DOI: 10.3791/3518-v • 13:47 min • April 23rd, 2012
April 23rd, 2012 •
*1,2, *1, 1,2, 1,2, 1,2
1Tumour Virology Division F010, German Cancer Research Center (DKFZ), 2Inserm Unit 701, German Cancer Research Center (DKFZ)
* These authors contributed equally

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Her beskriver vi en protokol baseret udelukkende på celle-infektion, hvilket forbedrer effektiviteten af ​​rekombinant parvovirus produktion med mere end 100 gange i sammenligning med andre protokoller, der anvendes. Denne protokol er afhængig af anvendelsen af ​​en hidtil ukendt adenovirus 5-baserede helper indeholdende parvovirus VP transkriptionsenhed (Ad-VP).

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Immunologi Recombinant parvovirus adenovirus virusproduktion pXX6 virus hjælper virologi onkologi
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