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Die Maus Forced Swim-Test
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Die Maus Forced Swim-Test

Article DOI: 10.3791/3638-v • 06:20 min • January 29th, 2012
January 29th, 2012 •
1, 2, 1, 3, 1, 1,3,4
1Department of Psychiatry, University of Maryland School of Medicine, 2Tulane University School of Medicine, 3Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, 4The Program in Neuroscience, University of Maryland

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Der Forced Swim Test wird als ein experimenteller Ansatz, um mögliche antidepressive Wirksamkeit in Nagetieren zu beurteilen validiert. Versuchstiere werden in einen Behälter mit Wasser und die Flucht-bezogene Mobilitätsverhalten gelegt wird quantifiziert. Das gemeinsame Verfahren für die Maus-Version dieses Tests sind beschrieben.

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Neuroscience Ausgabe 58 Tiermodelle Verhaltensanalyse Neurologie Neurobiologie affektive Störung Depression Stimmungsschwankungen Stabilisator antidepressiv forced swimming test FST
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