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Journal / Immunology and Infection / Engineering and Evolution af syntetisk…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Engineering and Evolution af syntetisk Adeno-associeret virus (AAV) Genterapivektorer via DNA Family blander
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Engineering and Evolution af syntetisk Adeno-associeret virus (AAV) Genterapivektorer via DNA Family blander

Article DOI: 10.3791/3819-v • 21:56 min • April 2nd, 2012
April 2nd, 2012 •
*1, *1, 2, 1, 1, 1, 1
1Cluster of Excellence CellNetworks, Department of Infectious Diseases, Virology, Heidelberg University, 2Department of Infectious Diseases, Virology, Heidelberg University
* These authors contributed equally

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Vi viser den grundlæggende teknik til molekylær konstruere og udvikle syntetiske Adeno-associerede virus (AAV) genterapivektorer via DNA familie blanding. Desuden leverer vi generelle retningslinjer og repræsentative eksempler på udvælgelse og analyse af individuelle kimære capsider med forbedrede egenskaber på målceller i kultur eller i mus.

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Immunologi adeno-associeret virus AAV genterapi syntetisk biologi viral vektor molekylær udvikling DNA shuffling
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