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A Murine Model of Muscle Training by Neuromuscular Electrical Stimulation
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A Murine Model of Muscle Training by Neuromuscular Electrical Stimulation

Article DOI: 10.3791/3914-v • 08:24 min • May 9th, 2012
May 9th, 2012 •
1,2,3, 2, 1,2, 1,2, 2
1Department of Physical Medicine and Rehabilitation, University of Pittsburgh, 2Department of Physical Therapy, University of Pittsburgh, 3McGowan Institute for Regenerative Medicine, University of Pittsburgh

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Summary
Automatic Translation

A murine model of neuromuscular electrical stimulation (NMES), a safe and inexpensive clinical modality, to the anterior compartment muscles is described. This model has the advantage of modifying a readily available clinical device for the purpose of eliciting targeted and specific muscle contractions in mice.

Tags

Murine Model Muscle Training Neuromuscular Electrical Stimulation NMES Skeletal Muscle Transcutaneous Surface Stimulation Motor Unit Muscle Fibers Myofiber Hypertrophy Muscle Strengthening Angiogenesis Growth Factor Secretion Muscle Precursor Cell Activation Stimulation Parameters Treatment Effect Fiber Type Contraindications Commercially Available Electrodes
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