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Modeling Colitis-Associated Cancer med Azoxymethane (AOM) og dextransulfat Natrium (DSS)
 
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Modeling Colitis-Associated Cancer med Azoxymethane (AOM) og dextransulfat Natrium (DSS)

Article DOI: 10.3791/4100-v 12:38 min September 11th, 2012
September 11th, 2012

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Summary

Please note that all translations are automatically generated.

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Vi viser en protokol, hvor administration af genotoksisk stof azoxymethane (AOM) efterfulgt af tre cyklusser af det pro-inflammatoriske middel dextransulfat-natrium (DSS) hurtigt og konsekvent frembringer colontumorer hos mus med morfologiske og molekylære lighed med dem, der ses i human colitis -associeret cancer.

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Medicin Cancer Biology Immunology Fysiologi Colitis Cancer dextransulfat Natrium Azoxymethane Inflammation Animal model Crohns sygdom
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