Neuroscience
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Trasfezione anticorpo in neuroni come strumento per studiare patogenesi della malattia
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Summary September 26th, 2012
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Un approccio rapido per investigare le interazioni e gli effetti sui meccanismi molecolari legati alla presenza di anticorpi in un ambiente intracellulare viene descritto. Il metodo comporta la transfezione di anticorpi nelle cellule vive utilizzando un non-covalente formazione del complesso basato su una formulazione lipidica. La tecnica è adattabile a linee cellulari immortalizzate e cellule primarie.
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