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Journal / Immunology and Infection / Glycosphingolipid Antijenler Kütle Spektrometrik…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Glycosphingolipid Antijenler Kütle Spektrometrik Analizi
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Glycosphingolipid Antijenler Kütle Spektrometrik Analizi

Article DOI: 10.3791/4224-v • 13:09 min • April 16th, 2013
April 16th, 2013 •
1, 2, 3,4
1Undergraduate Program, Rice University, 2Proteomics Facility, Department of Pathology, University of Texas MD Anderson Cancer Center, 3Department of Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, 4University of Texas Graduate School of Biological Sciences at Houston

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Bağışıklık, organlar ve hücreler içinde glycosphingolipid antijenlerin ekspresyonu profili içgörü kazanmak için bir spesifik ve duyarlı bir yöntem açıklanmıştır. Yöntem, kimyasal olarak sentezlenmiş bir standartlarına göre yapısal analizi için glycosphingolipid moleküllerinin adım adım parçalanma sağlayan iyon tuzak kütle spektrometri avantajına sahiptir.

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İmmünoloji Sayı 74 Biyokimya Moleküler Biyoloji Hücre Biyolojisi Yapısal Biyoloji Tıp Genetik Proteomik Proteinler Glycomics Fonksiyonel glycomics Glikosifingolipidler GSLs antijenler doğal öldürücü T hücreleri MALDI-TOF kütle spektrometresi LTQ iyon tuzağı kütle spektrometresi kütle spektrometresi glikolipitler lipidler
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