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Et analytisk verktøy som kvantifiserer Cellular Morfologi Endringer fra Tredimensjonal fluorescens bilder
Isolation of Microvascular Endothelial Tubes from Mouse Resistance Arteries
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Et analytisk verktøy som kvantifiserer Cellular Morfologi Endringer fra Tredimensjonal fluorescens bilder

Article DOI: 10.3791/4233-v • 10:00 min • August 31st, 2012
August 31st, 2012 •
1,2, 1, 1,3
1Medications Development, Ernest Gallo Clinic and Research Center, University of California, San Francisco, 2Clinical Pharmacology and Experimental Therapeutics, University of California, San Francisco, 3Translational Research Institute and the Institute for Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia

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Vi utviklet en programvare-plattform som utnytter Imaris Neuroscience, ImarisXT og MATLAB for å måle endringer i morfologi av en udefinert form hentet fra tre-dimensjonale confocal fluorescens av enkeltceller. Denne romanen tilnærmingen kan brukes til å kvantifisere endringer i cellen form etter reseptor aktivering og representerer derfor en mulig ekstra verktøy for medisiner.

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Cellular Biology 3-dimensjonal mikroskopi kvantifisering morfometriske single-celle dynamikk
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