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Journal / Immunology and Infection / Granulocyt-afhankelijke…
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Immunology and Infection
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Granulocyt-afhankelijke auto-antilichaam-geïnduceerde blaarvorming
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Granulocyt-afhankelijke auto-antilichaam-geïnduceerde blaarvorming

Article DOI: 10.3791/4250-v • 12:24 min • October 12th, 2012
October 12th, 2012 •
1, 2, 1,3
1Department of Dermatology, University of Freiburg, 2Kepler High School Freiburg, 3Centre for Biological Signalling Studies (BIOSS), University of Freiburg

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In het diermodel beschreven in onze huidige werk gezuiverde IgG antilichamen tegen een stuk van 200 aminozuren (aa 757-967) van collageen VII herhaaldelijk geïnjecteerd in muizen reproduceren blaarvorming fenotype en de histo-en immunopathologische kenmerken vertonen de menselijke epidermolysis bullosa acquisita (EBA)

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Immunologie Geneeskunde Fysiologie Anatomie Dermatologie auto-immuniteit collageen VII ontsteking extracellulaire matrix Fc-receptor complement granulocyt antilichaam
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