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Iteratieve optimalisatie van DNA-duplexen voor kristallisatie van SeqA-DNA complexen
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Iteratieve optimalisatie van DNA-duplexen voor kristallisatie van SeqA-DNA complexen

Article DOI: 10.3791/4266-v • 11:42 min • November 1st, 2012
November 1st, 2012 •
1, 1
1Department of Biochemistry and Biomedical Sciences, McMaster University

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Kristalstructuur van eiwit-DNA-complexen kan inzicht verschaffen in eiwitfunctie, mechanisme, evenals de aard van de specifieke interactie. Hier rapporteren we hoe de lengte en sequentie uiteinden van duplex DNA optimaliseren voor co-kristallisatie met

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Structural Biology SeqA DNA replicatie DNA zuivering eiwit-DNA-complexen proteïne-DNA cocrystallization röntgenkristallografie
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