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Modeling Hirnblutung in Mice: Injektion von Eigenblut oder bakterielle Collagenase

Article DOI: 10.3791/4289-v • 10:44 min • September 22nd, 2012
September 22nd, 2012 •
1, 1, 1, 1, 2, 1, 1,3,4
1Department of Physiology and Pharmacology, Loma Linda University School of Medicine, 2College of Natural and Agricultural Sciences, University of California, Riverside, 3Department of Anesthesiology, Loma Linda University School of Medicine, 4Department of Neurosurgery, Loma Linda University School of Medicine

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Klinisch relevante Tiermodelle Hirnblutung (ICH) sind notwendig, um unser Wissen über hämorrhagischen Schlaganfall zu erweitern und neue therapeutische Strategien zu untersuchen. In dieser Studie beschreiben wir und auswerten beiden ICH Modelle einseitige Injektionen von entweder autologe Vollblut oder bakteriellen Collagenase in den Basalganglien (Corpus striatum) von Mäusen implementieren.

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Medizin Ausgabe 67 Physiologie Neurowissenschaften Immunologie experimentellen Schlaganfall Tiermodell Eigenblut Kollagenase Hirnblutung Basalganglien Hirnverletzungen Ödeme Verhalten Maus
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