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清醒小鼠滴鼻的CNS药物治疗管理

JoVE Journal
Medicine

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JoVE Journal Medicine

Intranasal Administration of CNS Therapeutics to Awake Mice

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清醒小鼠滴鼻的CNS药物治疗管理

57,339 Views

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07:15 min

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April 08, 2013

DOI:

DOI:

•

07:15 min

April 08, 2013

•

81 Views

Leah R. Hanson¹, Jared M. Fine¹, Aleta L. Svitak¹, Katherine A. Faltesek¹

¹Alzheimer’s Research Center at Region’s Hospital,HealthPartners Institute for Education and Research

Summary

目的针对脑清醒小鼠鼻内给药的方法，进行说明。这种方法允许重复给药，长期使用鼻腔给药的药物无需麻醉，并以最小的全身暴露的鼻子到大脑传递。

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