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Journal / Medicine / L'endotelina-1 indotta cerebrale media…
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JoVE Journal Medicine
L'endotelina-1 indotta cerebrale media occlusione dell'arteria modello per l'ictus ischemico con guida laser flussimetria Doppler in Rat
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L'endotelina-1 indotta cerebrale media occlusione dell'arteria modello per l'ictus ischemico con guida laser flussimetria Doppler in Rat

Article DOI: 10.3791/50014-v • 07:26 min • February 16th, 2013
February 16th, 2013 •
1, 2, 1, 3, 4, 4, 1, 3
1Department of Neurosurgery, University of Florida, 2Department of Anatomical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran, 3Department of Physiology and Functional Genomics, University of Florida, 4Department of Neurology, University of Florida

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Modelli animali di ischemia cerebrale sono stati sviluppati per simulare la condizione umana di ictus. Questo protocollo descrive l'endotelina-1 (ET-1) indotta da occlusione dell'arteria cerebrale media (MCAO) modello per l'ictus ischemico nei ratti. Inoltre, importanti considerazioni, i vantaggi ei limiti di tale modello sono discussi.

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Medicina Numero 72 Neuroscienze Neurobiologia Ingegneria Biomedica Chirurgia Anatomia Fisiologia Malattie del Sistema Nervoso ictus ischemico endotelina-1 cerebrovascolare cervello arterie ictus occlusione laser doppley flussimetria ratto modello animale
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