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Journal / Medicine / Anvendelse af omvendt fase-protein Arrays (RPPA)…
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Anvendelse af omvendt fase-protein Arrays (RPPA) at udforske Protein Expression Variation i de enkelte renalcellecarcinom Kræft
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Anvendelse af omvendt fase-protein Arrays (RPPA) at udforske Protein Expression Variation i de enkelte renalcellecarcinom Kræft

Article DOI: 10.3791/50221-v • 12:23 min • January 22nd, 2013
January 22nd, 2013 •
1, 1, 1, 2, 3, 4, 4, 1,5, 6, 7, 1,2, 1
1Edinburgh Urological Cancer Group, University of Edinburgh, 2School of Medicine, University of St Andrews, 3Division of Pathology, University of Edinburgh, 4MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, 5Department of Pathology, Western General Hospital, 6Breakthrough Breast Cancer Research Unit, University of Edinburgh, 7St Bartholomew's Cancer Institute, Experimental Cancer Medicine Centre, Queen Mary University of London

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RPPA muliggør protein ekspression af hundreder af prøver, udskrives på nitrocellulose objektglas til at blive udspurgt samtidigt under anvendelse af fluorescensmærkede antistoffer. Denne teknik er blevet anvendt til at studere virkningen af ​​lægemiddelbehandling heterogenitet inden clear cell renal carcinoma.

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Cancer Biology Bioengineering medicin Biomedical Engineering Cellular Biology molekylærbiologi genetik Patologi Oncology Proteins tidlig påvisning af kræft Translationel Medical Research RPPA RCC heterogenitet Proteomics Tumor Grade intertumoral tumor metastatisk carcinoma renal cancer clear cell renal cell cancer cancer assay
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