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Journal / Neuroscience / Un método para la alta fidelidad Optogenética…
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Neuroscience

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JoVE Journal Neuroscience
Un método para la alta fidelidad Optogenética control de un individuo neuronas piramidales
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Un método para la alta fidelidad Optogenética control de un individuo neuronas piramidales

Article DOI: 10.3791/50291 • 13:44 min
September 2nd, 2013 •
*1,2, *1,2, 1,2
1Institute for Behavioral Genetics, University of Colorado Boulder, 2Department of Psychology and Neuroscience, University of Colorado Boulder
* These authors contributed equally

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September 2nd, 2013

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El reciente desarrollo de herramientas de la neurociencia, que combinan la genética y la óptica, denominada "optogenética", permite el control sobre la actividad de circuitos neuronales con un nivel sin precedentes de la resolución espacial y temporal. Aquí les ofrecemos un protocolo para la integración en la grabación vivo con la manipulación optogenética de subconjuntos definidos genéticamente las neuronas piramidales corticales y subicular prefrontales.

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