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Identifikation af Sygdomsrelaterede Spatial kovarians Opskrifter hvor neuroimaging data
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Identifikation af Sygdomsrelaterede Spatial kovarians Opskrifter hvor neuroimaging data

Article DOI: 10.3791/50319-v • 14:27 min • June 26th, 2013
June 26th, 2013 •
1, 1, 1, 1, 1, 1, 1
1Center for Neurosciences, The Feinstein Institute for Medical Research

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Multivariate teknikker, herunder principal komponent analyse (PCA) er blevet brugt til at identificere signatur mønstre af regional forandring i funktionelle billeder af hjernen. Vi har udviklet en algoritme til at identificere reproducerbare netværk biomarkører til diagnosticering af neurodegenerative sygdomme, vurdering af sygdomsprogression, og objektiv vurdering af behandlingseffekt hos patientpopulationer.

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Medicin neurobiologi Neuroscience anatomi fysiologi molekylærbiologi basalganglierne Sygdomme Parkinson lidelser Parkinsons sygdom bevægelsesforstyrrelser neurodegenerative sygdomme PCA SSM PET billedbehandling biomarkører funktionel hjernescanning multivariat rumlig kovariansanalyse global normalisering differential diagnose PD hjerne billedbehandling kliniske teknikker
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