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JoVE Journal
Biology

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高通量清醒小鼠肾小球滤过率的测定方法
 
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高通量清醒小鼠肾小球滤过率的测定方法

Article doi: 10.3791/50330
May 10th, 2013

Summary May 10th, 2013

Please note that all translations are automatically generated.

Click here for the English version.

肾小球滤过率(GFR)是测量评估肾功能的金标准。在这里,我们描述了一种高通量的方法,该方法允许由一个两阶段的指数衰减模型,通过使用一个单一的大剂量注射,测定异硫氰酸荧光素(FITC)在血浆中菊粉和肾小球滤过率的计算肾小球滤过率的测定在有意识的小鼠。

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