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In-vivo-Imaging der Tumorangiogenese mit Fluoreszenz-Videomikroskopie Konfokale
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In-vivo-Imaging der Tumorangiogenese mit Fluoreszenz-Videomikroskopie Konfokale

Article DOI: 10.3791/50347-v • 05:08 min • September 11th, 2013
September 11th, 2013 •
1, 1, 1,2, 1,2, 1,2, 1,2
1Université Paris Descartes Sorbonne Paris Cité, INSERM UMR-S970, 2Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Radiologie

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In diesem Beitrag stellen wir eine Methode, um Tumormikrogefäßen in vivo Analyse mit dynamischen Kontrastmittel-Fluoreszenz-Videomikroskopie. Zwei quantitative Parameter wurden erworben: funktionelle Kapillardichte was die Durchblutung des Tumors und Leckage Index spiegelt die Undichtigkeit der endothelialen Wand.

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Medizin Krebs Biologie Mikrozirkulation optische Imaging-Geräte (Design und Technik) konfokale Videomikroskopie Mikrozirkulation kapillares Leck FITC-Dextran Angiogenese
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