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Generatie van subcutane en Intrahepatic Human Hepatocellular carcinoom Xenografts in immunodeficiënte muizen
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Generatie van subcutane en Intrahepatic Human Hepatocellular carcinoom Xenografts in immunodeficiënte muizen

Article DOI: 10.3791/50544-v • 10:35 min • September 25th, 2013
September 25th, 2013 •
1, 1, 1, 1, 1, 2, 3, 1,3
1Toronto General Research Institute, University Health Network, 2Department of Pathology, University Health Network, 3Division of General Surgery, University Health Network

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Menselijke tumorxenotransplantaten in immunodeficiënte muizen zijn waardevolle instrumenten om kanker biologie studeren. Specifieke protocollen voor subcutane en intrahepatische xenograften uit menselijke hepatocellulair carcinoom cellen of tumorfragmenten genereren worden beschreven. Leverregeneratie geïnduceerd door gedeeltelijke hepatectomie in ontvangende muizen wordt gepresenteerd als een strategie om intrahepatische engraftment vergemakkelijken.

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Geneeskunde Lever Tumor hepatectomy diermodellen hepatocellulair carcinoom xenograft kanker lever subcutane intrahepatische orthotopische muis mens immunodeficiëntie
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