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Journal / Bioengineering / CometChip: A High-throughput di 96-Well…
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Bioengineering

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CometChip: A High-throughput di 96-Well Piattaforma per la misurazione dei danni cagionati DNA in cellule umane Microarrayed

Article DOI: 10.3791/50607-v • 10:59 min • October 18th, 2014
October 18th, 2014 •
*1, *2, 3, 1, 1, 2, 2, 1
1Department of Biological Engineering, Massachusetts Institute of Technology, 2Environmental Toxicology, Chulabhorn Graduate Institute, 3Department of Biomedical Engineering, University of Minnesota
* These authors contributed equally

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Descriviamo qui una piattaforma che consente di rilevare test della cometa di danno al DNA con velocità senza precedenti. Il dispositivo modelli di cellule di mammifero in un microarray e consente l'elaborazione parallela di 96 campioni. L'approccio facilita l'analisi del danno al DNA livello di base, danno al DNA indotto da esposizione e di riparazione del DNA cinetica.

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Bioingegneria test della cometa elettroforesi microarray danno al DNA riparazione del DNA
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