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Isolierung und chemische Charakterisierung von Lipid A von gramnegativen Bakterien
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Isolierung und chemische Charakterisierung von Lipid A von gramnegativen Bakterien

Article DOI: 10.3791/50623-v • 12:57 min • September 16th, 2013
September 16th, 2013 •
1, 2, 2, 1,3
1Section of Molecular Genetics and Microbiology, The University of Texas at Austin, 2Department of Chemistry and Biochemistry, The University of Texas at Austin, 3The Institute of Cellular and Molecular Biology, The University of Texas at Austin

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Isolierung und Charakterisierung der Lipid-A-Domäne von Lipopolysaccharid (LPS) von gramnegativen Bakterien gibt Einblick in Zelloberfläche basierend Mechanismen der Antibiotikaresistenz, bakterielle Überlebensrate und Fitness, und wie chemisch unterschiedlicher Lipid einer molekularen Spezies unterschiedlich modulieren Host angeborenen Immunantwort.

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Chemie Heft 79 Membranlipide Toll-Like Rezeptoren Endotoxine Glycolipide Lipopolysaccharide Lipid A Mikrobiologie Lipide Lipid A Bligh-Dyer Dünnschicht-Chromatographie (DC) Lipopolysaccharide Massenspektrometrie Collision induzierte Dissoziation (CID ) Photodissoziation (PD)
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