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A Computer-assisted Multi-electrode Patch-clamp System
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A Computer-assisted Multi-electrode Patch-clamp System

Article DOI: 10.3791/50630-v • 11:01 min • October 18th, 2013
October 18th, 2013 •
1, 1
1Laboratory of Neural Microcircuitry - Brain Mind Institute, Ecole Polytechnique Federale de Lausanne

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Summary
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Multi-electrode patch-clamp recordings constitute a complex task. Here we show how, by automating of many of the experimental steps, it is possible to accelerate the process leading to qualitative improvement in performance and number of recordings.

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Computer-assisted Multi-electrode Patch-clamp System Patch-clamp Technique Recording Electrical Activity Individual Neurons Subcellular Compartments Stable Recordings Time-consuming Procedure Complexity Automation Information Display Experimentalists Larger Number Of Recordings Greater Reliability Less Time Large-scale Recordings Simplify Experimental Steps Reduce Human Error Experimenter's Experience Visual Feedback Computer-assisted System Controls Multi-electrode Patch-clamp Experiment Single Interface Wireless Gamepad Experiment Related Information Guidance Cues
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