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Journal / Immunology and Infection / In vivo Imaging för att skilja akut och kronisk…
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Immunology and Infection

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In vivo Imaging för att skilja akut och kronisk inflammation
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In vivo Imaging för att skilja akut och kronisk inflammation

Article DOI: 10.3791/50690-v • 07:10 min • August 16th, 2013
August 16th, 2013 •
1, 2
1Lurie Family Imaging Center, Dana-Farber Cancer Institute, Harvard Medical School, 2Division of Pediatric Hematology/Oncology/Stem Cell Transplantation, Columbia University Medical Center

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Vi beskriver en icke-invasiv imaging metod för att särskilja inflammatoriska stadier. Systemisk tillförsel av luminol avslöjar områden med akut inflammation beroende av MPO-aktivitet i neutrofiler. Däremot tillåter injektion av lucigenin för visualisering av kronisk inflammation beroende Phox aktivitet i makrofager.

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Immunologi 78 infektion medicin cellbiologi molekylärbiologi Medicinsk teknik anatomi fysiologi Cancer Biology Stem Cell Biology Inflammation fagocyter fagocyter superoxider Molecular Imaging kemiluminescens, superoxid mareld kronisk inflammation akut inflammation fagocyter celler bildbehandling djurmodell
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