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Journal / Medicine / Microarray-baserte Identifikasjon av Individuell…
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Medicine

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JoVE Journal Medicine
Microarray-baserte Identifikasjon av Individuell Herv Loci Expression
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Microarray-baserte Identifikasjon av Individuell Herv Loci Expression: Søknad til biomarkører i Prostate Cancer

Article DOI: 10.3791/50713-v • 13:19 min • November 2nd, 2013
November 2nd, 2013 •
1,2, 1,2, 1,3,4, 1,2, 5, 1,4,6, 1,4,7, 1,2
1Joint Unit Hospices de Lyon-bioMérieux, 2Medical Diagnostic Discovery Department, BioMérieux, 3Department of Pathology and Cytology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, 4Medical Faculty, Lyon 1 University, 5Data and Knowledge Laboratory, BioMérieux, 6Department of Biochemistry and Molecular Biology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, 7Department of Urology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon

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Menneske endogene retrovirus (Herv), som opptar 8% av det menneskelige genom, beholde knappe koding kapasiteter, men hundre tusen lange terminal gjentar (ltr). En tilpasset Affymetrix microarray er designet for å identifisere individuelle Herv locus uttrykk og ble brukt på prostata kreft vev som en proof of concept for fremtidige kliniske studier.

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Medisin Cancer biologi genetikk molekylærbiologi prostata Retroviridae Biomarkører Farmakologisk tumor markører Biological prostatektomi microarray analyse Gene Expression Diagnose Menneskelig Endogene retrovirus Herv microarray transcriptome prostatakreft Affymetrix
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