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Journal / Immunology and Infection / 정제 된 조혈 줄기 / 전구 세포에 DNA 돌연변이를…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
정제 된 조혈 줄기 / 전구 세포에 DNA 돌연변이를 확인
The Lambda Select cII Mutation Detection System
Journal (Immunology and Infection)
The Lambda Select cII Mutation Detection System
Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay
Journal (Immunology and Infection)
Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay
 
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정제 된 조혈 줄기 / 전구 세포에 DNA 돌연변이를 확인

Article DOI: 10.3791/50752-v • 11:06 min • February 24th, 2014
February 24th, 2014 •
1, 1,2, 1, 3, 4,5, 2, 2,5, 1,2,5
1Greehey Children's Cancer Research Institute, UT Health Science Center at San Antonio, 2Department of Cellular and Structural Biology, UT Health Science Center at San Antonio, 3Department of Pathology, UT Health Science Center at San Antonio, 4Department of Microbiology, UT Health Science Center at San Antonio, 5Cancer Therapy and Research Center, UT Health Science Center at San Antonio

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여기서 우리는 LACI 유전자 변형 마우스 모델을 사용하여 정제 조혈 세포의 작은 숫자에 대한 생체 내 돌연변이 분석에 대해 설명합니다. LACI 유전자는 DNA의 돌연변이의 빈도, 위치 및 유형 자발적으로 일어 나 genotoxins에 노출 된 후를 결정하기 위해 분리 할 수있다.

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감염 호 (84) 조혈 줄기 / 전구 세포, DNA 돌연변이,
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