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Simulating Pancreatic Neuroplasticity: In Vitro Dual-neuron Plasticity Assay

Article DOI: 10.3791/51049-v • 10:29 min • April 14th, 2014
April 14th, 2014 •
1, 1, 2, 1, 1
1Department of Surgery, Klinikum rechts der Isar, Technische Universität München, 2Department of Biotechnology, University of Applied Sciences Kaiserslautern/Zweibrücken

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Summary
Automatic Translation

Neuronal plasticity is an increasingly recognized, but insufficiently understood feature of the gastrointestinal (GI) tract. Here, in the example of human pancreatic disorders, we present an in vitro neuroplasticity assay for the study of neuronal plasticity in the GI tract at both morphological and functional level.

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Pancreatic Neuroplasticity In Vitro Dual-neuron Plasticity Assay Enteric Nervous System Gastrointestinal Innervation GI Disorders Experimental Models Simulation Modulation Pancreatic Cancer Chronic Pancreatitis Newborn Rat Dorsal Root Ganglia Myenteric Plexus Organ-intrinsic Neuroplasticity Organ-extrinsic Neuroplasticity Neuronal Morphology Glial Morphology Electrophysiology Microenvironmental Contents
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