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Isolering og funktionel karakterisering af human Ventrikulær kardiomyocytter fra Fresh Kirurgiske Prøver
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Isolering og funktionel karakterisering af human Ventrikulær kardiomyocytter fra Fresh Kirurgiske Prøver

Article DOI: 10.3791/51116-v • 14:39 min • April 21st, 2014
April 21st, 2014 •
1, 2, 2, 1, 1, 1, 2, 1
1Department NeuroFarBa, Division of Pharmacology, University of Florence, 2Department of Clinical and Experimental Medicine, Division of Physiology, University of Florence

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Aktuel viden om den cellulære grundlag af hjertesygdomme meste afhængig af undersøgelser af dyremodeller. Her beskriver vi og validere en ny metode til at opnå en enkelt levedygtige cardiomyocytter fra små kirurgiske prøver af human ventrikulær myokardiet. Menneskelige ventrikelmyocytter kan bruges til elektrofysiologiske undersøgelser og narkotika testning.

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Medicine kardiologi hjerteceller elektrofysiologi excitation-kontraktion kobling handling potentiale calcium myokardiet hypertrofisk kardiomyopati hjertepatienter hjertesygdom
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