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Journal / Medicine / In Vivo Optical Imaging von Hirntumoren und…
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In Vivo Optical Imaging von Hirntumoren und Arthritis mit fluoreszierenden SapC-DOPS Nanovesicles
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In Vivo Optical Imaging von Hirntumoren und Arthritis mit fluoreszierenden SapC-DOPS Nanovesicles

Article DOI: 10.3791/51187-v • 09:04 min • May 2nd, 2014
May 2nd, 2014 •
1,2, 3, 1, 5,6, 5,6, 4, 4, 3, 1,2
1Division of Hematology-Oncology, Department of Internal Medicine, University of Cincinnati College of Medicine, 2Division of Human Genetics, University of Cincinnati College of Medicine, 3Department of Radiology, University of Cincinnati College of Medicine, 4Division of Rheumatology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 5Solid Tumor Biology Program, James Comprehensive Cancer Center, The Ohio State University Medical Center, 6Department of Neurological Surgery, James Comprehensive Cancer Center, The Ohio State University Medical Center

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Wir beschreiben eine Mehrfachwinkel-Dreh optischen Abbildungs ​​(Maroi)-System für die in vivo Quantifizierung einer Fluoreszenzmarkierung von Saposin C (SapC), Dioleoylphosphatidylserin (DOPS) nanovesicles geliefert. Der Einsatz Mausmodellen von Krebs und Arthritis, zeigen wir, wie die Signalkurve Maroi Analyse kann für die genaue Zuordnung und biologische Charakterisierung von Krankheitsprozessen eingesetzt werden.

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Medizin Saposin C (SapC) Dioleoylphosphatidylserin (DOPS) Hirntumor Arthritis Fluorophore Fluoreszenz Optical Imaging Multi-Winkel Dreh optische Bildgebung (Maroi)
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