Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
JoVE Journal
Bioengineering

A subscription to JoVE is required to view this content.

腺苷酸环化酶的药物引起的过敏性:含量简化和小型化的小分子和siRNA筛选应用
 
Click here for the English version

腺苷酸环化酶的药物引起的过敏性:含量简化和小型化的小分子和siRNA筛选应用

Article DOI: 10.3791/51218-v 09:39 min January 27th, 2014
January 27th, 2014

Chapters

Summary

Please note that all translations are automatically generated.

Click here for the English version.

持续激活的抑制性G蛋白偶联受体导致腺苷酸环化酶信令的致敏作用。以确定必需的分子途径,无偏差的方法是必要的,然而,这种策略需要一个可扩展的基于细胞的cAMP敏感测定法的发展。本文中,我们描述了一种致敏试验用于小分子和siRNA的筛选。

Tags

生物工程,83期,腺苷酸环化酶,腺苷,异敏,superactivati​​on,多巴胺D2,μ阿片类药物,RNA干扰
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter