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JoVE Journal Neuroscience
In vivo beeldvorming van Optic Nerve Fiber Integrity by-Contrast Enhanced MRI in Muizen
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In vivo beeldvorming van Optic Nerve Fiber Integrity by-Contrast Enhanced MRI in Muizen

Article DOI: 10.3791/51274-v • 11:38 min • July 22nd, 2014
July 22nd, 2014 •
*1, *2, 3, 3, 1, 2, 1, 2
1Hans Berger Department of Neurology, Jena University Hospital, 2Immunology, Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, 3Institute of Diagnostic and Interventional Radiology, Medical Physics Group, Jena University Hospital
* These authors contributed equally

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Deze video illustreert een methode, met behulp van een klinische 3 T scanner, voor contrast-versterkte MRI van de naïeve muis visuele projectie en voor herhaalde en longitudinale in vivo studies van de oogzenuw degeneratie geassocieerd met acute oogzenuw verpletteren letsel en chronische oogzenuw degeneratie in knock-out muizen (p50 KO).

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Neurowetenschappen ,-mangaan versterkte MRI muis retino-tectal projectie visuele systeem neurodegeneratie optische zenuw letsel NF-kB
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