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Journal / Immunology and Infection / Myeline Oligodendrocyte glycoproteïne (MOG
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Myeline Oligodendrocyte glycoproteïne (MOG
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Myeline Oligodendrocyte glycoproteïne (MOG

Article DOI: 10.3791/51275-v • 08:03 min • April 15th, 2014
April 15th, 2014 •
1,2, 1, 1, 1,3
1Department of Neurology, University of Münster, 2Interdisciplinary Center for Clinical Research (IZKF), Münster, 3Institute of Physiology – Neuropathophysiology, University of Münster

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Experimentele autoimmuun encefalomyelitis (EAE) is een gevestigde diermodel voor multiple sclerose. C57BL / 6 muizen worden geïmmuniseerd met myeline oligodendrocyt glycoproteïne (MOG) peptide 35-55 (MOG 35-55), wat resulteert in een oplopende zwakke verlamming veroorzaakt door autoreactieve immuuncellen in het centrale zenuwstelsel. Protocollen voor de ziekte van inductie en toezicht zal worden besproken.

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Immunologie experimentele autoimmuun encefalomyelitis EAE multiple sclerose MS diermodel Autoimmunity inflammatie centraal zenuwstelsel pertussis
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