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异位黏膜移植程序直接给药到小鼠的大脑

Article DOI: 10.3791/51452
July 16th, 2014 •
1, 1, 2
1Department of Biomedical Engineering, Boston University, 2Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School

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July 16th, 2014

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已开发人力内镜颅底重建的小鼠模型，会使用鼻腔粘膜移植大脑和鼻子之间的半透界面。这种方法使研究人员能够研究发货到全身给药时，被排除在外，否则由血脑屏障高分子量治疗中枢神经系统。

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