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Journal / Immunology and Infection / En fremgangsmåde til frembringelse Pulmonal…
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Immunology and Infection

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JoVE Journal Immunology and Infection
En fremgangsmåde til frembringelse Pulmonal Neutrofili Brug Aerosolized Lipopolysaccharid
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En fremgangsmåde til frembringelse Pulmonal Neutrofili Brug Aerosolized Lipopolysaccharid

Article DOI: 10.3791/51470-v • 08:33 min • December 15th, 2014
December 15th, 2014 •
1, 1, 1, 1, 1,2
1Department of Medicine, Solna and CMM, Respiratory Medicine Unit, Karolinska Institutet, 2Safety Science, Global Regulator Affairs & Patient Safety, AstraZeneca Global Medicines Development

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Vi beskriver en fremgangsmåde til at inducere neutrofil pulmonal inflammation ved udfordring aerosoliseret lipopolysaccharid ved forstøvning, at modellere akut lungeskade. Desuden er grundlæggende kirurgiske teknikker til lunge isolation, tracheal intubation og bronchoalveolær lavage også beskrevet.

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Immunologi akut lungeskade Airway inflammation Dyremodeller Bronchoalveolar lavage Lipopolysaccharid Neutrophils pulmonal levering sterile inflammation.
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