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Immunology and Infection

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JoVE Journal Immunology and Infection
Die Analyse der epithelialen Schäden Produziert von
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Die Analyse der epithelialen Schäden Produziert von

Article DOI: 10.3791/51668-v • 11:49 min • June 12th, 2014
June 12th, 2014 •
1, 2, 1, 1, 3, 1, 1
1Department of Infectomics and Molecular Pathogenesis, Center for Research and Advanced Studies of the National Polytechnic Institute, 2Department of Molecular Biomedicine, Center for Research and Advanced Studies of the National Polytechnic Institute, 3Agency for Knowledge Commercialization, Center for Research and Advanced Studies of the National Polytechnic Institute

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Die Infektion des Menschen durch Entamoeba histolytica führt zu Amöbenruhr, eine Hauptursache für Durchfall in tropischen Ländern. Infektion durch Pathogen-Interaktionen mit Darmepithelzellen eingeleitet, provoziert die Öffnung der Zell-Zell-Kontakte und somit Durchfall, manchmal gefolgt von Leberinfektion. Dieser Artikel bietet ein Modell, um die frühen Wirt-Pathogen-Interaktionen zu bewerten, um unser Verständnis der Pathogenese Amöbenruhr zu verbessern.

Tags

Immunologie , EhCPADH112 Zelladhäsion MDCK Caco-2 tight junction Störung Amöbenruhr Wirt-Pathogen-Interaktion Infektionsmodell Aktin-Zytoskelett
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