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In Vitro Pancreas Organogenese van Dispersed muis embryonale Progenitors
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In Vitro Pancreas Organogenese van Dispersed muis embryonale Progenitors

Article DOI: 10.3791/51725-v • 08:35 min • July 19th, 2014
July 19th, 2014 •
*1, *1, *2, 1,2
1Ecole Polytechnique Fédérale de Lausanne, School of Life Sciences, Swiss Institute for Experimental Cancer Research, 2DanStem, University of Copenhagen
* These authors contributed equally

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De driedimensionale cultuur methode beschreven in dit protocol recapituleert pancreas ontwikkeling van verspreide embryonale muis alvleesklier progenitoren, waaronder hun grote expansie, differentiatie en morfogenese in een vertakte orgaan. Deze methode is vatbaar voor beeldvorming, functiestoringen en manipulatie van de niche.

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Developmental Biology alvleesklier voorouders vertakking Epitheel Ontwikkeling Orgel Cultuur 3D Cultuur Diabetes Differentiatie Morfogenese Cell organisatie Beta Cell.
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