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Amida de reacción para la Síntesis de ligandos basados ​​en bispiridina y su complejación a Platinum como dinucleares Agentes anticancerígenos
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Amida de reacción para la Síntesis de ligandos basados ​​en bispiridina y su complejación a Platinum como dinucleares Agentes anticancerígenos

Article DOI: 10.3791/51740-v • 07:20 min • May 28th, 2014
May 28th, 2014 •
1, 2, 3, 4, 1
1Faculty of Pharmacy, The University of Sydney, 2School of Science and Health, University of Western Sydney, 3Division of Chemistry and Environmental Science, School of Science and the Environment, Manchester Metropolitan University, 4Nature Publishing Group

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Este protocolo describe el uso de reacciones de acoplamiento de amida del ácido isonicotínico y diaminoalcanos para formar ligandos puente adecuados para su uso en la síntesis de complejos de platino multinucleares, que combinan aspectos de los medicamentos contra el cáncer BBR3464 y picoplatin.

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Química BBR3464 picoplatin bispiridina acoplamiento de amida síntesis inorgánica cáncer
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