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Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence
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Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence

Article DOI: 10.3791/51815-v • 08:55 min • November 2nd, 2014
November 2nd, 2014 •
1, 1, 2, 3, 1, 1, 1, 1, 1, 1, 1
1Department of Obstetrics, Gynecology and Reproductive Sciences, Reproductive Immunology Unit, Yale University School of Medicine, 2NatureMost Laboratories, 3Bruker Preclinical Imaging

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Summary
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We describe a non-invasive animal imaging platform that allows the detection, quantification, and monitoring of ovarian cancer growth and recurrence. This intra-peritoneal xenograft model mimics the clinical profile of patients with ovarian cancer.

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Murine Model Non-invasive Imaging Detect Monitor Ovarian Cancer Recurrence Epithelial Ovarian Cancer Gynecologic Malignancy Surgical Debulking Combination Chemotherapy Platinum Compounds Taxane Compounds Chemoresistant Disease Novel Therapy Options Animal Models Clinical Profile Intra-peritoneal Disease I.p. Models Xenografts Optical Imaging Platform Optical Reporters Near Infrared 2-dimensional X-ray Co-registration Molecular Signals Rotation System
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