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Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence
JoVE Journal
Medicine
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JoVE Journal Medicine
Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence

Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence

DOI:
10.3791/51815-v

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08:55 min

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November 02, 2014

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, , , , , , , , , ,
1Department of Obstetrics, Gynecology and Reproductive Sciences, Reproductive Immunology Unit,Yale University School of Medicine, 2NatureMost Laboratories, 3Bruker Preclinical Imaging

Chapters

  • 00:05Title
  • 01:28Intra-uterine Injection of Human Ovarian Cancer Cells in Athymic Nude Mice
  • 04:21Detection of Early Stage Intra-peritoneal Ovarian Cancer by Live In Vivo Imaging
  • 07:22Results: Tumor Detection with Fluorescence Imaging
  • 08:24Conclusion

Summary

Automatic Translation

Automatic Translation

We describe a non-invasive animal imaging platform that allows the detection, quantification, and monitoring of ovarian cancer growth and recurrence. This intra-peritoneal xenograft model mimics the clinical profile of patients with ovarian cancer.

Tags

Ovarian CancerRecurrent DiseaseIntraperitoneal DiseaseXenograft ModelOptical ImagingNear-infraredMolecular ImagingTumor Growth MonitoringTherapy Evaluation

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