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Journal / Neuroscience / Neurônios olfativos obtida através Nasal Biópsia…
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JoVE Journal Neuroscience
Neurônios olfativos obtida através Nasal Biópsia Combinada com Laser-Capture Microdissection
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Neurônios olfativos obtida através Nasal Biópsia Combinada com Laser-Capture Microdissection: Uma Abordagem Potencial para tratamento estudo Response em Transtornos Mentais

Article DOI: 10.3791/51853-v • 08:33 min • December 4th, 2014
December 4th, 2014 •
1, 2, 1, 3, 2, 2, 4, 5, 1, 2
1Department of Psychiatry, Johns Hopkins University, 2Department of Psychiatry and Behavioral Sciences, Howard University, 3Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, 4Department of Psychiatry, Sheppard Pratt Hospital, 5Department of Psychiatry, Indiana University

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Neste estudo, um romance plataforma para investigar assinaturas moleculares intraneuronal de resposta ao tratamento do transtorno bipolar (TB) foi desenvolvido e validado. O epitélio olfatório de pacientes com TB foi obtido através de biópsias nasais. Em seguida, captura a laser microdissection foi combinado com Tempo real RT PCR para investigar a assinatura molecular de resposta de lítio em BD.

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Neurociência Edição 94 transtorno bipolar terapia com lítio a biópsia nasal olfato epitélio captura a laser microdissection PCR em tempo real,
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