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Journal / Immunology and Infection / Killer artificiale cellule presentanti…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Killer artificiale cellule presentanti l'antigene (KaAPC) per una efficiente
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Killer artificiale cellule presentanti l'antigene (KaAPC) per una efficiente

Article DOI: 10.3791/51859-v • 08:12 min • August 11th, 2014
August 11th, 2014 •
1, 2,3, 1, 1
1Department of Pathology, Institute of Cell Engineering, Johns Hopkins University, 2Department of Internal Medicine I, University of Regensburg, 3Department of Rheumatology, Asklepios Medical Center

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Orientamenti sono presentati per la generazione di antigene artificiale assassino cellule presentanti, KaAPC, uno strumento efficace per deplezione in vitro di cellule T antigene-specifiche umani e una soluzione alternativa per immunoterapia cellulare per il trattamento delle malattie autoimmuni mediate da cellule T in un antigene modo specifico senza compromettere il sistema immunitario rimanente.

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Immunologia autoimmunità l'apoptosi le cellule CD8 + T antigene-specifici HLA-A2-Ig Fas / FasL KaAPC
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